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For complete list:







Halikere A, Popova D, Scarnati M, Hamod A, Swerdel MR, Moores JC, Tischfield JA, Hart RP, and Pang ZP. Addiction associated N40D mu-opioid receptor variant modulates synaptic function in human neurons. Mol Psychiatry 2019 (in press)


Popova D, Desai N, Blendy J, Pang ZP. Synaptic regulation by OPRM1 variants in reward neurocircuitry. J Neurosci. 2019 May 20. pii: 2317-18. doi: 10.1523/JNEUROSCI.2317-18.2019. PMID: 31109961


Xu R, Brawner AT, Li S, Liu JJ, Kim H, Xue H, Pang ZP, Kim WY, Hart RP, Liu Y, Jiang P. OLIG2 Drives Abnormal Neurodevelopmental Phenotypes in Human iPSC-Based Organoid and Chimeric Mouse Models of Down Syndrome. Cell Stem Cell. 2019 May 14. pii: S1934-5909(19)30163-8. doi: 10.1016/j.stem.2019.04.014.


Fantuzzo JA, Hart RP, Zahn JD, Pang ZP. Compartmentalized Devices as Tools for Investigation of Human Brain Network Dynamics. Dev Dyn. 2019 Jan;248(1):65-77. doi: 10.1002/dvdy.24665.


Scarnati MS, Halikere A, Pang ZP. Using human stem cells as a model system to understand the neural mechanisms of alcohol use disorders: Current status and outlook. Alcohol. 2019 Feb;74:83-93. doi: 10.1016/j.alcohol.2018.03.008.





Liu JJ, Mirabella VR, Pang ZP. Cell type- and pathway-specific synaptic regulation of orexin neurocircuitry. Brain Res. 2018 Oct 5. pii: S0006-8993(18)30507-9. doi: 10.1016/j.brainres.2018.10.003


McGowan H, Mirabella V, Hamod A, Kayakhanyan A, Mlynark N, Moore JC, Tischfield JA, Hart RP and Pang ZP. hsa-let-7c miRNA regulates synaptic and neuronal function in human neurons, Front Synaptic Neurosci.2018,10:19.doi:10.3389/fnsyn.2018.00019


Zhang S, Moy W, Zhang H, Leites C, McGowan H, Shi J, Sanders A, Pang ZP, Gejman PV and Duan J. Open Chromatin Dynamics Reveals Stage-specific Transcriptional Networks in hiPSC-based neurodevelopmental model, Stem Cell Research, 2018 2018 Mar 31;29:88-98. doi: 10.1016/j.scr.2018.03.014.





Fantuzzo J, Mirabella V, Hamod A, Hart RP, Zahn J, Pang ZP. Intellicount: High-throughput quantification of synaptic protein puncta by machine learning, eNeuro, Nov/Dec, 4(6) e0219-17, 2017  67_Fantuzzo_eNeuro 2017


Liu JJ, Bello N, Pang ZP. Synaptic regulation by leptin in defined lateral hypothalamus–ventral tegmental area neurocircuitry is energy-state responsive, J Neurosci, 37(49):11854-11866, 2017 66_Liu_J Neurosci 2017


Liu J, Conde K, Zhang P, Lilascharoen V, Lim BK, Seeley R, Zhu JJ, Scott MM, Pang ZP. ­Enhanced AMPA receptor trafficking mediates the anorexigenic effect of endogenous glucagon like peptide-1 in the paraventricular hypothalamus, Neuron, 96(4): 897-909, 2017.65_Liu_Neuron 2017


Chemin J, Taiakina V, Monteil A, Piazza M, Guan W, Stephens RF, Kitmitto A, Pang ZP, Dolphin AC, Perez-Reyes E, Dieckmann T, Guillemette JG, Spafford JD. Calmodulin regulates Cav3 T-type channels at their gating brake. J Biol Chem; 292(49) 20010-20031, 2017. 64_Chemin_JBiol Chem 2017


Sun N, Nasello C, Deng L, Wang N, Zhang Y, Xu Z, Song Z, Kwan K, King RA, Pang ZP, Xing J, Heiman GA, Tischfield JA. The PNKD gene is associated with Tourette Disorder or Tic disorder in a multiplex family. Mol Psychiatry; 00, 1-9, 2017. 63_ Sun_Molecular Psychiatry 2017


Ong ZY, Liu JJ, Pang ZP, Grill HJ. Paraventricular Thalamic Control of Food Intake and Reward: Role of Glucagon-Like Peptide-1 Receptori signaling. Neuropsychopharmacology; 42: 2387-2397, 2017. 62_Ong_Neuropsycho pharmacology 2017


Forrest MP, Zhang H, Moy W, McGowan H, Leites C, Dionisio LE, Xu Z, Shi J, Sanders AR, Greenleaf WJ, Cowan CA, Pang ZP, Gejman PV, Penzes P and Duran J.  Open Chromatin Profiling in hiPSC-Derived Neurons Prioritizes Functional Noncoding Psychiatric Risk Variants and Highlights Neurodevelopmental Loci.  Cell Stem Cell; 21: 1-14, 2017. 61_Forest_Cell Stem Cell 2017


Joseph A. Fantuzzo JA, De Filippis L, McGowan H, Yang N, Ng YH, Halikere A, Liu JJ, Hart RP, Wernig M, Zahn JD and Pang ZP. μNeurocircuitry: establishing in vitro models of neurocircuits with human neurons, Technology; 5(2):87-95, 2017.  60_Joseph_Technology 2017


Lim CS, Kang X, Mirabella V, Zhang H, Bu Q, Araki Y Hoang ET, Wang S, Shen Y, Choi S, Kaang BK, Chagn Q, PangZP, Huganir RL, Zhu JJ. BRaf signaling principles unveiled by large-scale human mutation analysis with a rapid lentivirus-based gene replacement method. Genes Dev; 31(6): 537-552, 2017.





Xue Y, Qian H, Hu J, Zhou B, Zhou Y, Hu X, Karakhanyan A, Pang ZP and Fu XD.  Sequential regulatory loops as key gatekeepers for neuronal reprogramming in human cells.  Nat Neurosci, 19:807-815, 2016. 58_Xue_Nat Neurosci 2016


Liu J and Pang ZP.  Glucagon like peptide-1 drives energy metabolism on the synaptic highway.  FEBS Journal.  Invited State-of-the-Art Review, 2016. Liu_57_FEBS_2016


Hu P, Liu J, Yasrebi A, Gotthardt JD, Bello NT, Pang ZP and Roepke TA.  Gq-protein-Coupled Membrane-Initiated Estrogen Signaling Rapidly Excites Corticotropin-Releasing Hormone Neurons in the Hypothalamic Paraventricular Nucleus in Female Mice.  56_Hu_Endocrin 2016


Oni EN, Halikere A, Li G, Toro-Ramos AJ, Swerdel MR, Verpeut JL, Moore JC, Bello NT, Bierut LJ, Goate A, Tischfield JA, Pang ZP and Hart RP.  Increased nicotine response in iPSC-derived human neurons carrying the CHRNA5 N398 allele.  Sci Rep. 2016; 6:34341.  55_Oni_Sci Rep 2016


Nichola F, Bennett NK, Halikere A, Pang ZP and Moghe PV.  Self-assembling peptide nanofiber scaffolds for 3-D reprogramming and transplantation of human pluripotent stem cell-derived neurons.  ACS Biomater. Sci. Eng, 2016.54_Francis ACS Biomaterials2016


DeFilippis L, Halikere A, McGowan H, Moore JC, Tischfield JA, Hart RP and Pang ZP.  Ethanol-mediated activation of the NLRP3 inflammasome in iPS cells and iPS cells-derived neural progenitor cells.  Molecular Brain 9:51, 2016.53_DeFilippis_Mol Brain 2016


Carlson AL, Bennett NK, Francis NL, Halikere A, Clarke S, Moore JC, Hart RP, Paradiso K, Wernig M, Kohn J, Pang ZP and Moghe PV.  Generation and transplantation of reprogrammed human neurons in the brain using 3D microtopographic scaffolds. Nature Commun, 7:10862, 2016. 52_Carlson_Nature Communication 2016





Shreyas S, Liu JJ, Pasquale N, Lai J, McGowan H, Pang ZP and Lee KB.  Hybrid upconversion nanomaterials for optogenetic neuronal control.  Nanoscale, 7: 16571-16577, 2015.  51_Shreyas_Nanoscale 2015


DeFilippis L, Sudhof TC and Pang ZP.  Harness the power of endogenous neural stem cells by biomaterials to treat spinal cord injury.  Life Sciences China, November; 58: 1167-1168, 2015.  50_DeFilippis Life Sci China 2015


McGowan H and Pang ZP.  Regulatory functions and pathological relevance of the MECP2 3'UTR in the central nervous system.  Cell Regen (Lond), Oct 28; 4:9, 2015.  49_Pang_Cell Regen 2015


Wang XF, Liu JJ, Xia J, Liu J, Mirabella V and Pang ZP.  Endogenous glucagon-like peptide-1 suppresses high-fat food intake by reducing synaptic drive onto mesolimbic dipamine neurons.  Cell Report, 12, 1-8, 2015.  48 _Pang_Cell Reports 2015

Liu JJ, Mukherjee D, Haritan D, Ignatowska-Jankowska B, Liu J, Citri A and Pang ZP.  High on food:  the interaction between the neural circuits for feeding and for reward.  Front Biol, 10(2): 165-176, 2015.  47_Liu_Front Biol 2015




Wang Y, Ali Y, Lim CY, Hong W, Pang ZP and Han W.  Insulin-stimulated leptin secretion requires calcium and Pl3K/Akt activation.  Biochem J, 458(3): 491-8, 2014.  45_Wang_Biochem 2014


Wei S, Soh SL, Xia J, Ong WY, Pang ZP and Han W.  Motor neuropathy-associated mutation impairs Seipin functions in neurotransmission.  J Neurochem, 129(2): 328-38, 2014.  46_Wei_JournNeurochem 2014




Pertsinidis A, Mukherjee K, Sharma M, Pang ZP, Park SR, Zhang Y, Brunger AT, Sudhof TC and Chu S. Ultrahigh-resolution imaging reveals formation of neuronal SNARE/Munc18 complexes in situ. Proceedings of the National Academy of Sciences of the United States of America, 110(30), E2812–2820, 2013.  40_Pertsinidis_PNAS 2013

Zhou P, Pang ZP, Yang X, Zhang Y, Rosenmund C, Bacaj T and Südhof TC. Syntaxin-1 N-peptide and Habc-domain perform distinct essential functions in synaptic vesicle fusion. The EMBO journal, 32(1), 159–171, 2013. 17_Zhou_EMBOJ 2013

Guo J, Qiu W, Soh SLY, Wei S, Radda GK, Ong WY, Pang ZP and Han W. Motor neuron degeneration in a mouse model of seipinopathy. Cell death & disease, 4, e535. doi:10.1038/cddis.2013.64, 2013. 12_Guo_CDDIS 2013

Wei S, Soh SLY, Qiu W, Yang W, Seah CJY, Guo J, Ong WY, Pang ZP and Han W. Seipin regulates excitatory synaptic transmission in cortical neurons. Journal of neurochemistry, 124(4), 478–489. doi:10.1111/jnc.12099, 2013. 41_Wei_JournNeurochem 2013



Xu W, Morishita W, Buckmaster PS, Pang ZP, Malenka RC and Südhof TC. Distinct neuronal coding schemes in memory revealed by selective erasure of fast synchronous synaptic transmission. Neuron, 73:990-1001, 2012. 36_Xu_Neuron 2012

Pang ZP and Han W. Regulation of syanptic functions in central nervous system by endocrine hormones and the maintenance of energy homeostais. Biosci Rep. 2012. 24_Pang_BSR 2012



Citri A, Pang ZP, Wernig M, Südhof TC and Malenka RC*. Comprehensive qPCR profiling of gene expression in single neuronal cells, Nature Protocols, 7:118-127, 2012. 23_Ctriri_NPROT 2012

Marro S, Pang ZP, Yang N, Tsai MC, Qu K, change HY, Südhof TC and Wernig M. Direct lineage conversion of terminally differentiated hepatocytes to functional neurons. Cell Stem Cell, 9:374-382, 2011.   22_Marro_CellStemCell 2011

Pang ZP, Yang N, Vierbuchen T, Ostermeier A, Fuentes DR, Yang TQ, Citri A, Sebastiano V, Marro S, Südhof TC and Wernig M. Transcription factor-mediated induction of neurons from somatic and pluripotent human cells. Nature, 476(7359) :220-223, 2011.  18_Pang_Nature 2011

Pang ZP, Bacaj T, Yang XF, Zhou P and Südhof TC. Doc2 supports spontaneous synaptic transmission by a Ca2+-independent mechanism. Neuron, 70:244-251, 2011. 29_Pang_Neuron 2011

Deng P, Pang ZP, Lei ZG, Shikano S, Xiong Q, Harvey B, London B, Wang Y, Li M and Xu Z. Up-regulation of A-type Potassium Currents Protects Neurons against Cerebral Ischemia. Journal of Cerebral Blood Flow & Metabolism, 31(9):1823-1835, 2011. 15_Deng_JCBFM 2011

Yang N, Ng YH, Pang ZP, Südhof TC and Wernig M. Induced Neuronal Cells: how to make and define a neuron. Cell Stem Cell, 9:517-525, 2011. 13_Yang_CellStemCell 2011



Pang ZP, Xu W, Cao P and Südhof TC. Calmodulin suppresses synaptotagmin-2 transcription in cortical neurons. Journal of Biological Chemistry, 285: 33930-33939, 2010. 27_Pang_JBC 2010

Pang ZP, Cao P, Xu W and Südhof TC. Calmodulin controls synaptic strength via presynaptic activation of CaM Kinase II. Journal of Neuroscience, 30:4132-4142, 2010. 26_Pang_JNeurosci 2010

Pang ZP and Südhof TC.  Cell biology of Ca2+-triggered exocytosis. Current Opinion in Cell Biology, 22:496-505, 2010.  39_Pang_CurrenOpinion 2010

Vierbuchen T, Ostermeier A, Pang ZP, Kokubu Y, Südhof TC and Wernig M. Direct conversion of fibroblasts to functional neurons by defined transcription factors. Nature, 463:1035-1041, 2010. 19_Vierbuchen_Nature 2010

Yang XF, Kaeser-Woo YJ, Pang ZP, Xu W and Südhof TC. Complexin clamps fusion by blocking a secondary Ca2+-sensor via its accessory alpha-helix. Neuron, 68:907-920, 2010. 38_Yang_Neuron 2010

Sun T, Wu X, Xu J, McNeil B, Pang ZP, Yang W, Bai L, Qadri S, Molkentin J, Yue D and Wu LG. The role of calcium/calmodulin-activated calcineurin in rapid and slow endocytosis at central synapses. Journal of Neuroscience, 30:11838-11847, 2010. 32_Sun_JournNeurosci 2010

Shin OK, Lu J, Rhee JS, Tomchick DR, Pang ZP, Wojcik S, Camacho-Perez M, Brose N, Machius M, Rizo J, Rosenmund and Südhof TC. Munc13 C2B domain is an activity-dependent Ca2+-regulator of synaptic exocytosis. Nature Structural and Molecular Biology, 17:280-288, 2010. 31_Shin_NSMB 2010

Bacaj T, Pang ZP and Südhof TC. Testing the SNARE/SM protein model of membrane fusion. Proc Natl Acad Sci USA, 107:22365-22366, 2010. 35_Bacaj_PNAS 2010



Before 2009

Maximov A, Tang J, Yang X, Pang ZP, Südhof TC. Complexin controls the force transfer from SNARE complexes to membranes in fusion. Science, 323:516-521, 2009.  30_Maximov_Science 2009

Xu J, Pang ZP, Shin O-H and Südhof TC. Synaptotagmin-1 functions as Ca2+-sensor for spontaneous synaptic miniature release. Nature Neuroscience, 12:759-766, 2009. 37_XuJ_Nature Neurosci 2009

Deng P, Pang ZP, Lei Z and Xu ZC. Excitatory roles of protein kinase C in striatal cholinergic interneurons. Journal of Neurophysiology, 102:2453-2461,  2009. 14_Deng_JNeurophysiol 2009

Liang R, Pang ZP, Deng P and Xu ZC. Transient enhancement of inhibitory synaptic transmission in hippocampal CA1 pyramidal neurons after cerebral ischemia. Neuroscience, 160:412-418, 2009. 21_LiangR_Neurosci 2009

Sun J, Pang ZP, Qin D, Fahim AT, Adachi R and Südhof TC. A dual-Ca2+-sensor model for the neurotransmitter release in a central synapse. Nature, 450:676-682, 2007. 34_Sun_Nature 2007

Pang ZP, Shin OK, Meyer A, Rosenmund C and Südhof TC. A gain-of-function mutation in synaptotagmin-1 reveals a critical role of Ca2+-dependent SNARE-complex binding in synaptic exocytosis. Journal of Neuroscience, 26:12556-12565, 2006. 28_Pang_JNeurosci 2006

Wu H, Xu J, Pang ZP, Ge W, Kim KJ, Blanchi B, Chen C, Südhof TC and Sun YE. Integrative genomic and functional analyses reveal neuronal subtype differentiation bias in human embryonic stem cell lines. Proceedings of the National Academy of Sciences of the USA, 104:13821-13826, 2007. 42_Wu_PNAS 2007

Pang ZP, Melicoff E, Padgett D, Liu Y, Teich A, Dickey B, Lin W, Adachi R and Südhof TC. Synaptotagmin-2 is essential for survival and contributes to Ca2+-triggering of neurotransmitter release in central and neuromuscular synapses. Journal of Neuroscience, 26:13493-13504, 2006. 25_Pang_JNeurosci 2006

Pang ZP, Sun J, Rizo J, Maximov A, Südhof TC. Genetic analysis of synaptotagmin 2 in spontaneous and Ca2+-triggered neurotransmitter release. EMBO Journal, 25:2039-2050, 2006. 33_Pang_EMBO Journ 2006

Nagy G, Kim JH, Pang ZP, Matti U, Rettig J, Südhof TC, Sorensen JB. Different effects on fast exocytosis induced by synaptotagmin 1 and 2 isoforms and abundance but not by phosphorylation. Journal of Neuroscience, 26:632-643, 2006. 43_ Nagy_J Neuroscien 2006

Fan Y, Zou B, Ruan Y, Pang ZP and Xu ZC. In vivo demonstration of a late depolarizing postsynaptic potential in CA1 pyramidal neurons. Journal of Neurophysiology, 93:1326-1335, 2005. 10_Fan_JNeurophysiology 2005

Deng P, Pang ZP, Zhang Y and Xu ZC. Increase of delayed rectifier potassium currents in large aspiny neurons in the neostriatum following transient forebrain ischemia. Neuroscience, 2005, 131:135-146. 9_Deng_Neuroscience 2005

Wu MF, Pang ZP, Zhuo M and Xu ZC. Prolonged membrane potential depolarization in cingulate pyramidal cells after digit amputation in adult rats. Molecular Pain, 1:23, 2005. 44_Wu_Molecular Pain 2005

Deng P, Pang ZP, Zhang Y and Xu ZC. Developmental changes of transient potassium currents in large aspiny neurons in the neostriatum. Developmental Brain Research, 153:97-107, 2004. 8_Deng_DevBrainRes 2004

Pang ZP, Ling GY, Gajendiran M and Xu ZC. Asymmetric changes of excitatory transmission in spiny neurons following transient forebrain ischemia after dopamine depletion. Neuroscience, 114:317-326, 2002. 7_Pang_Neuroscience 2002

Pang ZP, Deng P, Ruan YW and Xu ZC. Depression of fast excitatory synaptic transmission in striatal large aspiny neurons after transient forebrain ischemia. Journal of Neuroscience, 22:10948-10957, 2002. 6_Pang_JNeurosci 2002

Gajendiran M, Ling GY, Pang ZP and Xu ZC. Differential changes of synaptic transmission in spiny neurons of rat neostriatum following transient forebrain ischemia. Neuroscience, 105:139-152, 2001. 4_Gajendiran_Neuroscience 2001

Pang ZP, Ling GY, Gajendiran M and Xu ZC. Enhanced excitatory synaptic transmission in spiny neurons of rat striatum after unilateral dopamine denervation. Neuroscience Letter, 308:201-205, 2001. 5_Pang_Neurosci Letter 2001

Kiyosawa A, Katsurabayashi S, Akaike N, Pang ZP and Akaike N. Nicotine facilitates glycine release in the rat spinal dorsal horn. Journal of Physiology (Lond), 536:101-110, 2001. 3_Kiyosawa_JPhysiology 2001

Xu TL, Pang ZP, Li JS and Akaike N. 5-HT potentiation of the GABAA response in the rat sacral dorsal commissural neurons. British Journal of Pharmacology, 124:779-787, 1998. 2_Xu_Brit JPhar 1998

Wang DS, Xu TL, Pang ZP, Li JS and Akaike N. Taurine-activated chloride currents in rat sacral dorsal commissural neurons. Brain Research, 792:41-47, 1998.  1_Wang_BrainRes 1998




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